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Year : 2017  |  Volume : 9  |  Issue : 1  |  Page : 1-5

Pathological perspective of chondrocyte apoptosis in osteoarthritis


1 Department of Orthopaedics, Institute of Medical Sciences, BHU, Varanasi, Uttar Pradesh, India
2 Department of Pathology, Institute of Medical Sciences, BHU, Varanasi, Uttar Pradesh, India

Correspondence Address:
Mohan Kumar
Department of Pathology, Institute of Medical Sciences, BHU, Varanasi - 221 005, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-7341.207173

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Osteoarthritis constitutes a major burden for health care besides posing great impediments to quality of life in progressively widening population of the aged. There have been on-going efforts to rationally address the preventive and corrective interventions. Destruction of articular cartilage is a cardinal consideration in this regard. The dilemma persists over that being a cause or effect of the osteoarthritic syndrome. The aging diseases are typically accompanied by comorbidities and decline in physiological functions. This article appraises the pathological process of cartilage destruction in such context to reflect on interventional perspectives ahead.


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